10 Most Expensive Drugs in The World

by Priyanka Kabra 29.08.22

10. Spinraza (API Nursinersen)

[{"selector":"#anim-d9d3769d-93ad-4987-822e-8363fc4284f6","keyframes":{"opacity":[0,1]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-2f46db4f-31f9-4069-a6f8-9553b5ec079a","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-de9dfa80-6ab4-46ae-9b61-ee84f75fe7ac","keyframes":{"opacity":[1,1]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-f0820f09-4254-4680-91d0-59b595cd3036","keyframes":{"transform":["scale(3)","scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Used to treat a disease named Spinal Muscular Atrophy (SMA). SMA occurs due to a mutation on a fifth chromosome (5q) characterized by progressive muscle atrophy that starts shortly after birth. pic credit @pmlive.com

9. Lumizyme (API Alglucosidase alfa)

[{"selector":"#anim-116acc6f-b167-4cb4-af10-f8e5e369f951","keyframes":{"opacity":[0,1]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-66d986ca-5351-4c7c-96c8-04698bb45e0b","keyframes":{"transform":["translate3d(0px, 461.64610%, 0)","translate3d(0px, 0px, 0)"]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Used to treat Pompe disease (rare, inherited disorder). This disease ultimately leads to impaired function of the muscles and liver. pic credit @ lumizyme.com

8. Elaprase (API Idursulfase)

[{"selector":"#anim-e2a45c60-f536-4b6a-953b-ec3e3a4f4aab","keyframes":{"opacity":[0,1]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8c0410e1-0be8-4a26-a311-e2e0d5e8b301","keyframes":{"transform":["translate3d(0px, 692.46898%, 0)","translate3d(0px, 0px, 0)"]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Used to treat a rare inherited disease that affects only males- Hunter syndrome which causes walking and breathing difficulties. pic credit @elaprase.com

7. Brineura (API Cerliponase alfa)

[{"selector":"#anim-66093aae-1b8e-4443-87a1-0ab9dd5907da","keyframes":{"opacity":[0,1]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-eca76d98-7d9f-4a26-ad3d-bb2012608393","keyframes":{"transform":["translate3d(0px, 692.46898%, 0)","translate3d(0px, 0px, 0)"]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Used to treat a rare inherited disease that affects only males- Hunter syndrome which causes walking and breathing difficulties.

6. Soliris (API Eculizumab)

[{"selector":"#anim-90d87944-6522-4767-9d19-748b8afac119","keyframes":{"opacity":[0,1]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e368dd25-e043-4a03-aef4-a374fd1aab68","keyframes":{"transform":["translate3d(0px, 720.24677%, 0)","translate3d(0px, 0px, 0)"]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Used to treat a rare group of diseases that affect red blood cells.

5. Carbaglu (API Carglumic acid)

[{"selector":"#anim-7596ef4b-ac63-4906-a61f-14fd0d0917d2","keyframes":{"opacity":[0,1]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-606cd71c-d640-4179-9fd9-b7cef57fc550","keyframes":{"transform":["translate3d(0px, 370.53500%, 0)","translate3d(0px, 0px, 0)"]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Used to treat a rare group of diseases that affect red blood cells. pic credit @empr.com

4. Ravicti (API Glycerol Phenylbutyrate)

[{"selector":"#anim-50de95ef-149e-496a-bfef-50ebf3882fc3","keyframes":{"opacity":[0,1]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-87f72660-3566-4920-acbc-c2fd2d44c0e8","keyframes":{"transform":["translate3d(0px, 363.12756%, 0)","translate3d(0px, 0px, 0)"]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] U sed to treat patients with urea cycle disorders (UCDs) pic credit @ravicti.com

3. Luxturna (API Voretigene neparvovec)

[{"selector":"#anim-3453891f-921c-4869-be72-01b8af50c17e","keyframes":{"opacity":[0,1]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f68e6c7b-e3db-4d4a-aa8a-159d266acfd1","keyframes":{"transform":["translate3d(0px, 391.27572%, 0)","translate3d(0px, 0px, 0)"]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] U sed to treat patients with urea cycle disorders (UCDs)

2. Zokinvy (API Ionafarnib)

[{"selector":"#anim-055f0ec1-abc9-4c4f-b1d4-89c0fd9afdc7","keyframes":{"opacity":[0,1]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a01c78ab-8f3e-4aa4-b403-8b2ed936a5ef","keyframes":{"transform":["translate3d(0px, 723.58006%, 0)","translate3d(0px, 0px, 0)"]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Used to treat Hutchinson-Gilford Progeria Syndrome. HGPS is an extremely rare disorder which results in young people aging quickly, which results in the death of most patients before the age of 15 years from heart diseases. pic credit @empr.com

1. Zolgensma (API Onasemnogene abeparvovec-xioi)

[{"selector":"#anim-65e69905-2695-4fb1-bbe0-7962d0424685","keyframes":{"opacity":[0,1]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b6c89a6c-803a-4e37-aa7a-5fccd5360882","keyframes":{"transform":["translate3d(0px, 373.05090%, 0)","translate3d(0px, 0px, 0)"]},"delay":100,"duration":2000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] It is the most expensive drug in the world. It comes in the form of suspension for intravenous infusion and targets children under the age of 2 with Spinal Muscular Atrophy ( SMA). pic credit @theguardian.com

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10 Most Expensive Drugs in The World

10. Spinraza (API Nursinersen)

Annual cost of treatment: $375,000 ($750,000 in the first year). Manufacturer: Biogen, American multinational biotechnology company.

9. Lumizyme (API Alglucosidase alfa)

Minimum annual cost of treatment: $520,000 ( can go up to $625,000). Manufacturer: Sanofi Genzyme, MA, US.

8. Elaprase (API Idursulfase)

Price per 6mg: $4,215, and annual treatment for a child weighing 35kg is $657,000. Manufacturer: the Shire, Ireland

7. Brineura (API Cerliponase alfa)

Annual cost of treatment: $700,000. Manufacturer: BioMarin Pharmaceutical Inc, U.S.

6. Soliris (API Eculizumab)

The cost per vial: $6,830 Annual cost can reach up to $700,000. Manufacturer: Alexion Pharmaceuticals Inc. USA

5. Carbaglu (API Carglumic acid)

The price for 5 tablets: $1,040, Annual treatment cost can come to $790,000 Manufacturer: Recordati, Italy

4. Ravicti (API Glycerol Phenylbutyrate)

Each 25mL vial costs $5,016 Annual cost of treatment can reach up to $794,000. Manufacturer: Horizon Pharma GmbH, Germany

3. Luxturna (API Voretigene neparvovec)

It is a one-time treatment with a price $850,000. Manufacturer: Novartis, Switzerland.

2. Zokinvy (API Ionafarnib)

Annual cost of treatment: $1,032,480 Manufacturer: Eiger BioPharmaceuticals

1. Zolgensma (API Onasemnogene abeparvovec-xioi)

It is a one-time treatment with a price $2,125,000. Manufacturer: Novartis, Switzerland.

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